Experts Meeting on Gynecologic Oncology May 19-21, 2016 San Antonio,Texas, USA

There are many factors that cause Gynecologic cancers. Medical research has discovered that some classes of genes, called Oncogenes and tumorsuppressor genes promote the growth of cancer. The abnormal function of these genes can be acquired (e.g., through smoking, aging, Environmental influences) or inherited. Almost all cervical cancers and some cancers of the vagina and vulva are caused by a virus known as HPV (Human Papilloma virus).

Gynecologic cancer can’t be detected normally and risk increases with age, so it’s important to go for regular health checkups from which it can be recognised. Symptoms are not same for every individual and every gynecologic cancer, like In some cases Vaginal bleeding which is unusual and it might be vaginal, cervical and uterine cancer. In other cases symptoms like Pelvic pressure which might be Ovarian, Uterine and Vulvar. Bloating and Abdominal back pain which might be a symptom of ovarian cancer. Itching/burning of the Vulva will be present in Vulvar cancer.

Among all gynecologic cancers only cervical cancer has a screening test—the Pap test—that can find this cancer early. When treatment works best it helps in prevention of cervical cancer for finding pre-cancers. HPV Test looks for Human Papilloma virus infection which can be used along with the Pap test for screening women aged 30 years and older. It also provides more information when Pap test results are unclear for women aged 21 and older. Robotic surgery and miniature instruments were used to enhance a gynecologic oncologist’s laparoscopic skills when removing a patient’s uterus and cervix.

Gynecologic cancers are treated by using one or more of the following ways such as surgery that is by removal of cancer tissue, Radiation Therapy alone or combined with chemotherapy that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from further dividing. . The choice of treatment therapies depends on the type & stage of the cancer. In generally a gynecologic cancer patient often treated with combined therapies for efficient results.  

Breast cancer is the most common invasive cancer in females worldwide. It accounts for 16% of all female cancers and 22.9% of invasive cancers in women. 18.2% of all cancer deaths worldwide, including both males and females, are from breast cancer.Breast cancer rates are much higher in developed nations compared to developing ones. There are several reasons for this, with possibly life-expectancy being one of the key factors - breast cancer is more common in elderly women; women in the richest countries live much longer than those in the poorest nations. The different lifestyles and eating habits of females in rich and poor countries are also contributory factors, experts believe

Ovarian cancer is most common in women who have been through the menopause (usually over the age of 50), although it can affect women of any age.As the symptoms of ovarian cancer can be similar to those of other conditions, it can be difficult to recognise. However, there are early symptoms to look out for, such as persistent bloating, pain in the pelvis and lower stomach, and difficulty eating. The treatment you receive for ovarian cancer will depend on several things, including the stage of your cancer and your general health. Chemotherapy is the main treatment for ovarian cancer, but your treatment will usually involve a combination of surgery and chemotherapy

Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ in women where fetal development occurs. Endometrial cancer is often detected at an early stage because it frequently produces abnormal vaginal bleeding, which prompts women to see their doctors. If endometrial cancer is discovered early, removing the uterus surgically often cures endometrial cancer. Endometrial cancer can spread to other parts of your body, making it more difficult to treat successfully. Endometrial cancer that spreads (metastasizes) most often travels to the lungs.

Cervical cancer is a type of cancer that develops in a woman's cervix (the entrance to the womb from the vagina).Cancer of the cervix often has no symptoms in its early stages. If you do have symptoms, the most common is unusual vaginal bleeding, which can occur after sex, in between periods or after the menopause. Almost all cases of cervical cancer are caused by the human papilloma virus (HPV). HPV is a very common virus that can be passed on through any type of sexual contact with a man or a woman. Treatment may include surgery, radiation therapy, chemotherapy, or a combination. The choice of treatment depends on the size of the tumor.

Uterine cancer is the most common cancer of a woman’s reproductive system. Uterine cancer begins when normal cells in the uterus change and grow uncontrollably, forming a mass called a tumor. A tumor can be cancerous or benign. A cancerous tumor is malignant, meaning it can spread to other parts of the body. There are two major types of uterine cancer 1)Adenocarcinoma. This makes up more than 80% of uterine cancers. It develops from cells in the lining of the uterus called the endometrium. 2)Sarcoma type of uterine cancer develops in the supporting tissues of the uterine glands or in the myometrium, which is the uterine muscle.

Vulvar cancer is a rare type of cancer. It forms in a woman's external genitals, called the vulva. The cancer usually grows slowly over several years. First, precancerous cells grow on vulvar skin. This is called vulvar intraepithelial neoplasia (VIN), or dysplasia. Not all VIN cases turn into cancer, but it is best to treat it early. Radiation therapy may be used in more advanced vulvar cancer cases when disease has spread to the lymph nodes and/or pelvis. It may be performed before or after surgery.Women with vulvar cancer should have routine follow-up and exams with their oncologist, often every 3 months for the first 2–3 years after treatment. They should not have routine surveillance imaging to monitor the cancer unless new symptoms appear or tumor markers begin rising.Imaging without these indications is discouraged because it is unlikely to detect a recurrence or improve survival and is associated with its own side effects and financial costs

The implementation of new drug treatments has improved the prognosis for advanced cancers of the cervix, uterus, and ovary. Platinum analogs are the most effective drugs in the treatment of ovarian cancer. Fertility drugs (FD) are spreading worldwide fast and therefore many studies have reviewed the possible association between the use of these drugs and cancer. Since the drugs used for ovulation induction during in vitro fertilization (IVF) like hCG, hMG, rFSH increase the levels of gonadal hormones, concerns have grown regarding the risk of developing cancer in breast, ovary, endometrium, and other target organs.If the treatment plan involves chemotherapy you may experience physical, emotional, and/or psychological side effects related to this treatment. The side effects of ovarian cancer treatment depend on the type of treatment and may be different for each woman. 

Gestational trophoblastic disease (GTD) is the general name for a group of rare tumors that occur during pregnancy in the fetalchorion, GTD can occur in any kind of pregnancy which is almost always curable if found early. Uterine leiomyosarcoma (LMS) is a rare uterine malignancy it is an aggressive tumor associated with a high risk of recurrence and death, regardless of stage.Choriocarcinoma is a cancer that develops most commonly from abnormal placenta and it is nearly 100% curable if appropriate chemotherapy is administered after the tumor mass is separated from inside the uterus. 

The surgical methods include- Initial Debulking surgery,   which may be performed by variety of procedures depending on the type & stage of ovarian cancer based on individual fertility concerns. The procedure for removal of ovary and fallopian tubes is known as Bilateral salpingo-oophorectomy surgery. The surgical removal of uterus and cervix is known as. Total hysterectomy. Lymph node biopsy will be performed by collecting the fluid sample from the abdomen. Omentectomy is surgical process for removing of omentum partially or as a whole. Fold of fatty tissue inside the abdomen is known as Omentum

The problems with sexuality and fertility persist for women treated for cervical cancer despite these advances. Sexual dysfunction following treatment for gynecologic cancer has been well documented in the literature, and recent studies demonstrate the success of brief psychosexual interventions. Treatment of sexual difficulties in cancer patients can be achieved through the provision of information, support, and symptom management, ideally as part of a sexual health program. Resources are not always available to develop such a program. However, medical professionals can identify individuals and organizations with expertise in treating sexual and fertility concerns, which can be provided to their patients, making help with these problems more accessible as needs arise.

In endometrial cancer, MRI is used to identify myometrial invasion and extrauterine disease, allowing preoperative surgical planning in women with serious comorbidity. In cervical cancer, MRI has an established role in local staging. By assessing the proximal extension of tumours in young women, MRI determines the feasibility of fertility-preserving surgery. It is also used to plan and administer radiotherapy. This optimises tumour radiation, while limiting unwanted radiation to the bowel and other pelvic organs. In ovarian cancer, MRI is useful in young women as it is superior to ultrasound in diagnosing endometriomas, dermoids and fibroids, which can be misdiagnosed by ultrasound as malignant lesions.

The vast majority of the lesions that occur in the breast are benign. Much concern is given to malignant lesions of the breast because breast cancer is the most common malignancy in women in Western countries; however, benign lesions of the breast are far more frequent than malignant ones .With the use of mammography, ultrasound, and magnetic resonance imaging of the breast and the extensive use of needle biopsies.Most importantly, a pregnant woman with cancer is capable of giving birth to a healthy baby because cancer rarely affects the fetus directly. Although some cancers may spread to the placenta, most cancers cannot spread to the baby. However, being pregnant with cancer is extremely complicated for both the mother and the health care team. Transfusion of one or more of the components of whole blood. The blood components may have been taken from the patient previously (autologous transfusion) or donated by someone else (homologous transfusion). Except in the case of acute hemorrhage, the transfusion of whole blood is rarely needed.

The suitable Screening and self-examinations conducted regularly can result in the detection of certain types of gynecologic cancers for successful treatment in their early stages. Proper Nutrient diet, physical exercise and standard of living choices play a significant role in the prevention of cancer. Over and above, awareness of family history can increase the chance of prevention or early diagnosis for to detect any gene susceptible to cancer. 

A Gynecologic oncologist is an obstetrician/gynecologist who specializes in the diagnosis and treatment of women with cancer of the reproductive organs.Specifically, the gynecologic oncologist treats cancer of the ovary, endometrium, uterus, cervix, vagina, vulva and trophoblastic disease. If chemotherapy is indicated, the same gynecologic oncologist is capable of administering treatment.

A key ingredient in successful entrepreneurship is self-knowledge. Gynecologic Oncology 2016 aims to bring together all existing and budding bio entrepreneurs to share experiences and present new innovations and challenges in Gynecological community. Each year, over a million companies are started in the world with about 5–10 of them classified as high technology companies. Turning ideas into business ventures is tricky and the opportunity-recognition step is critical in new venture creation. This gestalt in the entrepreneur's perception of the relationship between the invention and final product is refined into a business model that describes how the venture will make money or provide an appropriate return to the potential investors. gynecologic cancers is complex and rapidly changing and requires a specialized knowledge to understand the value of the innovation and its competitive position in the industry. Although life scientists are typically the founders of biotech companies, studies have shown that the most successful high tech startups are founded by a team of two to three individuals with mixed backgrounds, substantial industry experience and a very clear market and product focus at founding. This three day community-wide conference will be a highly interactive forum that will bring experts in areas ranging from Gynecological Oncology to signaling pathways to novel therapeutic approaches to the scientific hub. In addition to our outstanding speakers, we will also showcase short talks and poster presentations from submitted abstracts.The speakers will discuss All these five different types of gynecologic cancers risk increases with the age. When these cancers were diagnosed at their early stages, the treatment will be more efficient. The five major types of cancer affect a woman's reproductive organs are ovarian, uterine, cervical,vulvar, and vaginal.